00000nam 2200000zi 4500 9.907038 CaOODSP 20240214102643 m o d f cr mn||||||||| 220118e202203 onca ob f000 0 eng d 9780660416830 9780660416847 (incorrect) CaOODSP eng rda CaOODSP n-cn--- H144-98/2022E-PDF Lung cancer and ambient PM2.5 in Canada : a systematic review and meta-analysis. Ottawa, ON : Health Canada = Santé Canada, March 2022. ©2022 1 online resource (vii, 51 pages) : illustrations (some colour) text txt rdacontent computer c rdamedia online resource cr rdacarrier The original publication file in PDF format was replaced with an accessible version on 14-02-2024 at the request of Health Canada. Issued also in French under title: Cancer du poumon et PM2,5 ambiantes au Canada : revue systématique et méta-analyse. "Pub.: 210602." Includes bibliographical references (pages 26-28). "In Canada, lung cancer is the most commonly diagnosed cancer, with a five-year survival rate under 20%. Fine particulate matter (PM2.5) is an important environmental risk factor for lung cancer. Additionally, the International Agency of Research for Cancer (IARC) determined that ambient particulate matter (PM) is a Group 1 carcinogen (2016), Health Canada (2013) concluded that chronic exposure to PM likely causes lung cancer mortality, and the US EPA (2019) concluded that the relationship between long-term exposure to PM2.5 and cancer was likely to be causal. Systematic review and meta-analysis methodology was implemented to provide quantitative evidence that long-term exposure to PM2.5 is associated with an increased risk of lung cancer specific to Canada. Additional qualitative evidence was provided to characterize other additional factors (such as confounders, effect modifiers, and the shape of the concentration-response curve) that may further contextualize the relationship of interest"--Abstract, page vii. Lungs Cancer Risk factors Canada. Lungs Cancer Mortality Canada. Particulate matter Health aspects Canada. Carcinogens Canada. Canada. Health Canada, issuing body. Cancer du poumon et PM2,5 ambiantes au Canada : (CaOODSP)9.907041 PDF 2.33 MB https://publications.gc.ca/collections/collection_2022/sc-hc/H144-98-2022-eng.pdf